Pharmacological Effects of Garlic (Allium sativum L.)
نویسندگان
چکیده
Singh VK, Singh DK. Pharmacological Effects of Garlic (Allium sativum L.). ARBS Annu Rev Biomed Sci 2008;10:6-26. Garlic (Allium sativum L.) is a bulbous herb used as a food item, spice and medicine in different parts of the world. Its medicinal use is based on traditional experience passed from generation to generation. Researchers from various disciplines are now directing their efforts towards discovering the effects of garlic on human health. Interest in garlic among researchers, particularly those in medical profession, has stemmed from the search for a drug that has a broad-spectrum therapeutic effect with minimal toxicity. Recent studies indicate that garlic extract has antimicrobial activity against many genera of bacteria, fungi and viruses. The role of garlic in preventing cardiovascular disease has been acclaimed by several authors. Chemical constituents of garlic have been investigated for treatment of hyperlipidemia, hypertension, platelet aggregation and blood fibrinolytic activity. Experimental data indicate that garlic may have anticarcinogenic effect. Recent researches in the area of pest control show that garlic has strong insecticidal, nematicidal, rodenticidal and molluscicidal activity. Despite field trials and laboratory experiments on the pesticidal activity of garlic have been conducted, more studies on the way of delivery in environment and mode of action are still recommended for effective control of pest. Adverse effects of oral ingestion and topical exposure of garlic include body odor, allergic reactions, acceleration in the effects of anticoagulants and reduction in the efficacy of anti-AIDS drug Saquinavir. ©by São Paulo State University ISSN 1806-8774
منابع مشابه
Therapeutic Uses and Pharmacological Properties of Garlic, Shallot, and Their Biologically Active Compounds
Objective(s): Garlic (Allium sativum L. family Liliaceae) is well known in Iran and its leaves, flowers, and cloves have been used in traditional medicine for a long time. Research in recent decades has shown widespread pharmacological effects of A. sativum and its organosulfur compounds especially Allicin. Studies carried out on the chemical composition of the plant show that the ...
متن کاملPharmacological effects of traditional herbal plant garlic (Allium sativum): A review Paudel KR
This study aimed to review the different pharmacological effects of garlic. Garlic, Allium sativum, is a herbal plant which has been used in different food preparations since long time. Many studies have shown that allicin is the main compound in garlic which is generated from alliin with the help of alliinase enzyme and is responsible for many pharmacological effects. Different studies have sh...
متن کاملEffect of garlic (Allium sativum) extract on levels of urea and uric acid in normal and streptozotocin-diabetic rats
The effects of garlic bulbs alcoholic extract (Allium sativum) on the level of urea and uric acid were investigated in both normal and streptozotocin-induced diabetic rats. The normal and diabetic rats were administrated orally with the extract (100, 250, 500 mg/kg) or glibenclamide (600 mg/kg) for 14 days. Oral administration of the garlic extract (0.25 and 0.5 g/kg body wt.) for 14 days exhib...
متن کاملShort communication: Effects of garlic (Allium sativum L) extract on growth, feed utilization and carcass composition in Mugil cephalus (Linnaeus, 1758) larvae
متن کامل
Effect of garlic (Allium sativum) extract on levels of urea and uric acid in normal and streptozotocin-diabetic rats
The effects of garlic bulbs alcoholic extract (Allium sativum) on the level of urea and uric acid were investigated in both normal and streptozotocin-induced diabetic rats. The normal and diabetic rats were administrated orally with the extract (100, 250, 500 mg/kg) or glibenclamide (600 mg/kg) for 14 days. Oral administration of the garlic extract (0.25 and 0.5 g/kg body wt.) for 14 days exhib...
متن کامل